Michael Guzman

Contact information

Lawrence Livermore National Laboratory
7000 East Avenue, L-452
Livermore, CA 94550
email: guzman30@llnl.gov
phone: 925 424 5734




PhD, Molecular Genetics and Genomics, Washington University in St. Louis, 2019
BS, Biology, Portland State University, 2013


My research interests lie at the intersection of microbial metabolism, genomics, and geomicrobiology. I am broadly interested in bacterial physiology and how it influences the geochemistry of the Earth (geomicrobiology), and how we can leverage these interactions for biotechnology (applied microbial physiology). Currently, I am using an interdisciplinary approach to study microbe-mineral interactions towards developing sustainable bio-cement through microbially-mediated processes. This work integrates microbial physiology, biochemistry, geochemistry and microbial ecology to address an important engineering problem.

My graduate work was to apply classical genetic combined with omic, bioelectrochemical, and geochemical approaches to investigate the physiology of “electricity-eating” bacteria. I investigated the bioenergetic underpinnings of electrode oxidation by photoautotrophic purple nonsulfur bacteria, including Rhodopseudomonas palustris TIE-1. This work combined electron transfer biophysics, microfluidics, and microscopy to investigate the electron flow pathway from a cathode into TIE-1 cells as well as stable isotope geochemistry, molecular genetic, and systems-level approaches to demonstrate that cathode-oxidation is linked to autotrophic CO2 fixation.


Guzman MS, Karthikeyan R, MM Binkley, Jones C, Ranaivoarisoa T, Singh R, DA Fike, JM Meacham, Bose A. Phototrophic extracellular electron uptake is linked to carbon dioxide fixation in the bacterium Rhodopseudomonas palustrisNature Communications, 10(1355), (2019).

Ranaivoarisoa T, Singh R, Karthikeyan R, Guzman MS, Bose A. Towards sustainable bioplastic production using the photoautotrophic bacterium Rhodopseudomonas palustris TIE-1. Journal of Industrial Microbiology & Biotechnology. (2019).

Gupta D, Guzman MS, Bose A. Draft Genome Sequence of a Marine Photoferrotrophic Bacterium, Rhodovulum robiginosum DSM 12329T. Microbiology Resource Announcements, 8(8), e01684-18 (2019).

Guzman MS, Bose A. Draft Genome Sequences of Four Rhodobacter sphaeroides Strains Isolated from a Marine Ecosystem. Microbiology Resource Announcements, 8(3), e01648-18 (2019).

Guzman MS, Kuse JC, Santiago-Merced N, Bose A. Draft Genome Sequences of Two Closely Related Marichromatium Isolates, Photosynthetic Gammaproteobacteria from Marine Ecosystems. Microbiology Resource Announcements, 8(2), e01510-18 (2019).

Singh R, Guzman MS, Bose A. Anaerobic oxidation of ethane, propane and butane by marine microbes: A mini review. Frontiers in Microbiology, 8, 2056 (2018).

Guzman MS, McGinley B, Santiago-Merced N, Gupta D, Bose A. Draft genome sequences of three closely related isolates of the purple nonsulfur bacterium Rhodovulum sulfidophilum. Genome Announcements. 5.11, e00029-17 (2017).

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