Jonathan Bethke

Contact information

Lawrence Livermore National Laboratory
7000 East Avenue, L-452
Livermore, CA 94550
phone: 925 423 7437



Ph.D. in Molecular Genetics and Microbiology, Duke University, 2022
B.S. in Biology, University of Virginia, 2013


I research how we can manipulate bacterial evolution to preserve or create new functions, with particular focus on horizontal gene transfer at population and community levels.

Recent publications

  1. Jonathan H. Bethke, Helena R. Ma, Ryan Tsoi, Li Cheng, Minfeng Xiao, and Lingchong You. Vertical and horizontal gene transfer tradeoffs direct plasmid fitness. Mol. Syst. Biol. 1, (2022).

  2. Jonathan H. Bethke, Adam Davidovich, Li Cheng, Allison J. Lopatkin, Wenchen Song, Joshua T. Thaden, Vance G. Fowler Jr., Minfeng Xiao, and Lingchong You. Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli. Sci. Adv. 6, (2020).