The Systems and Synthetic Biology Group

We focus on designing microbes and microbial communities for clean energy and improved safeguards for the environment and human health.  We use systems biology approaches to gain a predictive understanding of complex biological systems and uncover foundational design rules that govern system behavior.  Synthetic biology enables rational genome-scale redesign of organisms/communities and construction of biological systems with desired traits for specific applications.  Multidisciplinary approaches that cover molecular biology, biochemistry, and “omics” are used to investigate microbes and microbial communities as they respond to perturbations, especially those relevant to emerging issues in bioenergy, bioremediation, and pathogenesis.